Paediatric glaucoma, connective tissue disease Eye Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Between 1 month and 16 years of age 2. Having eye pressure measurements as part of their care 3. Willing to have GAT and RBT measurements 4. Has glaucoma or a connective tissue disorder, or no eye disease (no eye surgery/medication, no high spectacle prescription i.e < +/- 6.00 DS and < -2.00D astigmatism)
Exclusion criteria
Exclusion criteria: 1. Subjects who are unwilling to have GAT and RBT measurements 2. Subjects who have known allergies to proxymetacaine or fluorescein eye drops 3. Pregnant subjects 4 Babies born prematurely 5. High spectacle prescription in eyes with no disease (> +/- 6.00 DS and > -2.00D astigmatism)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure (IOP) measured in mmHg at the centre of the cornea of children with glaucoma and at 3mm temporal to the centre of the cornea by the Icare rebound tonometer. Following this, IOP is then measured by Goldman tonometer. This is undertaken within approximately 20 minutes at one visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraocular pressure (IOP) measured in mmHg at the centre of the cornea of healthy children and children with connective tissue disease and at 3mm temporal to the centre of the cornea by the Icare rebound tonometer. Following this, IOP is then measured by Goldman tonometer in mmHg. This is undertaken within approximately 20 minutes at one visit. The following additional data will be noted at the same time: refraction in diopters, visual acuity in LogMar, central corneal curvature in mm, central corneal thickness µm, axial length in mm, age in years. | — |
Countries
United Kingdom