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The validity and reliability of intraocular pressure measurement using rebound tonometry in young children

The validity and reliability of intraocular pressure measurement using rebound tonometry in young children: observational cross-sectional study and case-control study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN15954407
Enrollment
50
Registered
2017-08-17
Start date
2016-05-31
Completion date
Unknown
Last updated
2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatric glaucoma, connective tissue disease Eye Diseases

Interventions

Intraocular pressure measurement in children using the Icare rebound tonometer. To examine the accuracy and reliability of the RBT (Aims 1, 2 and 3) the children will undergo three IOP

Sponsors

Aston University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Between 1 month and 16 years of age 2. Having eye pressure measurements as part of their care 3. Willing to have GAT and RBT measurements 4. Has glaucoma or a connective tissue disorder, or no eye disease (no eye surgery/medication, no high spectacle prescription i.e < +/- 6.00 DS and < -2.00D astigmatism)

Exclusion criteria

Exclusion criteria: 1. Subjects who are unwilling to have GAT and RBT measurements 2. Subjects who have known allergies to proxymetacaine or fluorescein eye drops 3. Pregnant subjects 4 Babies born prematurely 5. High spectacle prescription in eyes with no disease (> +/- 6.00 DS and > -2.00D astigmatism)

Design outcomes

Primary

MeasureTime frame
Intraocular pressure (IOP) measured in mmHg at the centre of the cornea of children with glaucoma and at 3mm temporal to the centre of the cornea by the Icare rebound tonometer. Following this, IOP is then measured by Goldman tonometer. This is undertaken within approximately 20 minutes at one visit.

Secondary

MeasureTime frame
Intraocular pressure (IOP) measured in mmHg at the centre of the cornea of healthy children and children with connective tissue disease and at 3mm temporal to the centre of the cornea by the Icare rebound tonometer. Following this, IOP is then measured by Goldman tonometer in mmHg. This is undertaken within approximately 20 minutes at one visit. The following additional data will be noted at the same time: refraction in diopters, visual acuity in LogMar, central corneal curvature in mm, central corneal thickness µm, axial length in mm, age in years.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026