Skip to content

Does adding intravenous dexamethasone to paravertebral block augment postoperative analgesia in breast cancer patients?

Intravenous dexamethasone augments the analgesic effect of paravertebral block for cancer breast surgery: a prospective randomised placebo-controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN15920148
Enrollment
100
Registered
2017-06-29
Start date
2017-03-01
Completion date
Unknown
Last updated
2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female patients undergoing surgery for breast cancer Surgery Surgery for breast cancer

Interventions

Participants are randomly allocated to one of two groups. Participants receive the standard operating care prior to surgery. Intervention group: Participants in this group receive a p

Sponsors

National Cancer Institute, Cairo University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Patients for breast cancer surgery ASA1-3 2. Aged from 18-80

Exclusion criteria

Exclusion criteria: 1. Coagulopathy 2. Allergy to drugs in study 3. Refusal to participate 4. Severe renal, hepatic or lung disease 5. Chronic opioid use

Design outcomes

Primary

MeasureTime frame
1. Pain is measured using the visual analogue score (VAS) at every two hours during the 72 hours post operation 2. Time of return sensation is measures using patient interviews at every two hours during the 72 hours post operation 3. Analgesic taken is measured using patient records at every two hours during the 72 hours post operation

Secondary

MeasureTime frame
1. Nausea is measured using patient records at every two hours during the 72 hours post operation 2. Vomiting is measured using patient records at every two hours during the 72 hours post operation 3. Side effects and complications measured using patient records at every two hours during the 72 hours post operation

Countries

Egypt

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 22, 2026