Dental caries Oral Health
Conditions
Interventions
Histological study:
A randomized, triple-blinded, single-center, split-mouth, active-controlled clinical trial with two arms. Two pediatric experienced pediatric dentists (ICC >0.8) recruited 24 patie
Sponsors
Damascus University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Histological study: Cooperative patients aged 8-10 years requiring serial extraction and pulpotomy of first primary molars Clinical and radiographical study: Cooperative patients aged 5-10 years requiring pulpotomy of second primary molars
Exclusion criteria
Exclusion criteria: Histological study: Compromised patients or patients with signs and symptoms of pulp necrosis or spontaneous and/or nocturnal pain history in first primary molars Clinical and radiographical study: Compromised patients or patients with signs and symptoms of pulp necrosis or spontaneous and/or nocturnal pain history in second primary molars
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The following primary outcomes will be measured using histology after 7, 30, and 90 days: 1. Odontoblastic integrity 2. Pulp tissue hemorrhage 3. Pulp fibrosis 4. Dentin bridge formation 5. Pulp calcification The following primary outcomes will be measured using clinical evaluation after 3, 6, and 12 months: 1. Spontaneous pain 2. Pain on percussion 3. Tooth mobility 4. Abscess 5. Fistula 6. Exfoliation of the treated tooth The following primary outcomes will be measured using radiographical evaluation after 3, 6, and 12 months: 1. Furcal radiolucency 2. Internal root resorption 3. External root resorption 4. Widening of the periodontal ligament 5. Canal obliteration 6. Dentin bridge formation | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
Syria
Contacts
Public ContactMawia Karkoutly
Outcome results
None listed