Colorectal cancer Cancer
Conditions
Interventions
This study has two key elements
an observational, population-based study (data work stream) and a prospective cohort study (for the tissue and patient reported outcome measures (PROMS)).
The data work stream of the study is an ob
Sponsors
University of Leeds
Eligibility
Sex/Gender
All
Age
18 Years to 120 Years
Inclusion criteria
Inclusion criteria: For the observational, population-based aspects of the study: 1. A diagnosis of bowel cancer (ICD 10 code C18, 19 or C20) 2. Resident in the Yorkshire and Humber region and managed by one of the sixteen bowel cancer MDTs who are participating in the study. For prospective cohort aspects of the study: 1. A diagnosis of bowel cancer (ICD 10 code C18, 19 or C20) 2. Close to the time of diagnosis and before primary treatment commences (unless the individual presents urgently and undergoes an emergency resection) 3. Considered suitable for treatment 4. English literate
Exclusion criteria
Exclusion criteria: 1. Patients under 18 years of age 2. Patients with a diagnosis of anal cancer (ICD-10 code C21) 3. Patients who are not-resident within Yorkshire and the Humber study region and who have not been diagnosed and managed by one of the 16 bowel cancer MDTs who participating in the study 4. In addition for the prospective cohort aspects will exclude patient who lacks the capacity to give informed consent (this may be due, for example, to psychopathology, cognitive dysfunction or learning difficulties)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bowel cancer survival across Yorkshire and Humber in context of treatment and socio-demographics, assessed using datasets from the Public Health England National Cancer Registration and Analysis Service (NCRAS) covering 2014-2021. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life, measured using standardised and tested questionnaires including EORTC, EQ-5D-5L, Social Difficulties Inventory, The Short Warwick-Edinburgh Mental Well-being Scale, Self Efficacy for Managing Chronic Disease scale, The Brief Illness Perceptions Questionnaire measured at diagnosis and 12-months following diagnosis. | — |
Countries
England, United Kingdom
Contacts
Public ContactHannah Rossington
Outcome results
None listed