The short and long-term consequences of critical illness on the heart and blood vessels

The short and long-term cardiovascular consequences of critical illness: The C3 Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN15905609

Enrollment

80000

Registered

2020-09-10

Start date

2020-09-01

Completion date

Unknown

Last updated

2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major adverse cardiovasular events and arrhythmia Circulatory System

Interventions

This is a retrospective cohort study of major adverse cardiovascular events and arrythmias in survivors of critical illness treated on an intensive care unit in the UK.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients admitted to a general adult intensive care unit at one or more of the study sites between 01/01/2006 and 01/08/2023.

Exclusion criteria

Exclusion criteria: 1. Patients that have informed their participating site that they do not wish their electronic records would be used for future research 2. Patients who inform us directly that they don’t wish their records used in this research study

Design outcomes

Primary

Measure	Time frame
Measured using electronic healthcare records at 5 years post-discharge from ICU: 1. Mortality 2. Major adverse cardiovascular and vascular events 3. Arrhythmia	—

Secondary

Measure	Time frame
Hospital re-admission measured using electronic healthcare records at 5 years post-discharge from ICU	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026