The nutrition, cardiovascular wellness and diabetes project

Conditions

1. Obesity 2. Type 2 diabetes 3. Atherosclerosis 3. Hypertension 4. Liver steatosis 5. Thyroid diseases 6. Tumors 7. Cognitive impairment Nutritional, Metabolic, Endocrine 1. Obesity 2. Type 2 diabetes 3. Atherosclerosis 3. Hypertension 4. Liver steatosis 5. Thyroid diseases 6. Tumors 7. Cognitive impairment

Buscemi C, Randazzo C, Barile AM, Caldarella R, Malavazos AE, Caruso R, Colombrita P, Lombardo M, Buscemi S.

2025-10-23

10.1038/s41387-025-00394-7

Factors associated with body weight gain and insulin-resistance: a longitudinal study

Carola Buscemi, Cristiana Randazzo, Anna Maria Barile, Simona Bo, Valentina Ponzo et al. (11 authors)

Nutrition and Diabetes2024-04-2210 citations

10.1038/s41387-024-00283-5

Influence of Habitual Dairy Food Intake on LDL Cholesterol in a Population-Based Cohort

Silvio Buscemi, Davide Corleo, Carola Buscemi, Cristiana Randazzo, Antonio Maria Borzì et al. (15 authors)

Nutrients2021-02-1113 citations

10.3390/nu13020593

Serum Irisin Concentrations in Severely Inflamed Patients

Silvio Buscemi, Davide Corleo, Sonya Vasto, Carola Buscemi, Anna Maria Barile et al. (9 authors)

Hormone and Metabolic Research2020-02-2012 citations

10.1055/a-1111-9249

Prevalence and severity of nonalcoholic fatty liver disease by transient elastography: Genetic and metabolic risk factors in a general population.

Petta S, Di Marco V, Pipitone RM, Grimaudo S, Buscemi C, Craxì A, Buscemi S.

2018-05-0771 citations

10.1111/liv.13743

Factors associated with circulating concentrations of irisin in the general population cohort of the ABCD study.

Buscemi S, Corleo D, Vasto S, Buscemi C, Massenti MF, Nuzzo D, Lucisano G, Barile AM, Rosafio G, Maniaci V, Giordano C.

2017-10-1331 citations

10.1038/ijo.2017.255

Interventions

The 2011 study was an observational, cross-sectional study carried out in Palermo, the largest city in Sicily, Italy. From March 28th to April 10th 2011, groups composed of physicians (n= 5) and dieti

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 years or over 2. Residents in Palermo area (Italy) 3. Having been part of the 2011 cohort or being a new participant introduced by a participant to the 2011 study (up to a maximum of 300 new participants)

Exclusion criteria

Exclusion criteria: N/A

Design outcomes

Primary

Measure	Time frame
1. Insulin resistance measured using HOMA-Index [fasting blood concentrations of insulin (mU/L) x glycemia (mmol/L) / 22.5], at baseline and 4 years from the first observation 2. Carotid atherosclerosis measured using ecography to measure the carotid intima-media thickness. This is measured at baseline and 4 years from the first observation	—

Secondary

Measure	Time frame
1. Changes to the number and size of thyroid nodules are measured using ecography at baseline and 4 years from the first observation 2. Liver stenosis is measured by determining liver stiffness and controlled attenuation parameter (CAP) using a fibroscan at baseline and 4 years from the first observation 3. The level of mild cognitive impairment will be determined using mini-Mental State Examination (MMSE) score and clock-test score at baseline and 4 years from the first observation	—

Measure

Time frame

1. Changes to the number and size of thyroid nodules are measured using ecography at baseline and 4 years from the first observation 2. Liver stenosis is measured by determining liver stiffness and controlled attenuation parameter (CAP) using a fibroscan at baseline and 4 years from the first observation 3. The level of mild cognitive impairment will be determined using mini-Mental State Examination (MMSE) score and clock-test score at baseline and 4 years from the first observation

—

Countries

Italy

Contacts

Public ContactSilvio Buscemi

silvio.buscemi@unipa.it+3 991 655 4580

Outcome results

None listed