The effect of exercise on fasting insulin and fitness levels in people with spinal cord injury: Development of evidence-based exercise programs

A randomized controlled trial of six-weeks combined exercise program on fasting insulin and fitness levels in individuals with spinal cord injury

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN15824294

Enrollment

Registered

2017-05-31

Start date

2014-04-04

Completion date

Unknown

Last updated

2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal cord injury Nervous System Diseases Spinal cord injury

Interventions

Participants will be randomized to one of two groups using the minimization method. Intervention group: Participants will receive a 6-week combined exercise program. Participants will exercise for 6

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. An SCI >6 months 2. Age between 18 and 65 years 3. No regular exercise over the prior six months

Exclusion criteria

Exclusion criteria: 1. Cardiovascular disease 2. Uncontrolled type 2 diabetes 3. Uncontrolled hypertension 4. Pressure ulcers 5. Orthopedic problems

Design outcomes

Primary

Measure	Time frame
1. Fasting glucose is measured using ADVIA 1650 Chemistry System at baseline and six weeks 2. Insulin is measured using Roche Chemistry System at baseline and six weeks 3. Insulin resistance will be estimated according to the homeostasis model assessment of insulin resistance (HOMA-IR) index at baseline and six weeks	—

Secondary

Measure	Time frame
1. Total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C) levels will be measured using an ADVIA 1650 Chemistry System at baseline and six weeks 2. Upper body strengh will be measured by a hand-held dynamometer at baseline and six weeks 3. Vo2 peak will be assessed through maximal graded exercise tests, performed using a ramp protocol at baseline and six weeks. 4. Quality of life will be measured using the SF-36 questionnaire at baseline and six weeks 5. Anxiety and depression will be measured using the Generalized Anxiety Disorder 7-item (GAD-7) scale and Patient Health Questionnaire (PHQ-9) at baseline and six weeks	—

Measure

Time frame

1. Total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C) levels will be measured using an ADVIA 1650 Chemistry System at baseline and six weeks 2. Upper body strengh will be measured by a hand-held dynamometer at baseline and six weeks 3. Vo2 peak will be assessed through maximal graded exercise tests, performed using a ramp protocol at baseline and six weeks. 4. Quality of life will be measured using the SF-36 questionnaire at baseline and six weeks 5. Anxiety and depression will be measured using the Generalized Anxiety Disorder 7-item (GAD-7) scale and Patient Health Questionnaire (PHQ-9) at baseline and six weeks

—

Countries

Korea, South

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026