Post-supratentorial craniotomy pain Signs and Symptoms Acute pain
Conditions
Interventions
Participants are allocated to one of four groups. All patients receive morphine-based patient controlled analgesia for 24 hours following surgery, in addition to one of the following:
1. Intravenous d
Sponsors
University of Istanbul
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiology (ASA) classification I-II or III 2. Aged 18 - 70 2. Scheduled for elective supratentorial craniotomy
Exclusion criteria
Exclusion criteria: 1. Neurological disorders hindering communication 2. Aphasia 3. Glasgow Coma Score (GCS) less than 15 4. Drug or alcohol addiction 5. Chronic pain 6. Raised intracranial pressure 7. Allergies to any of the drugs used in this study 8. Hepatic or renal dysfunction 9. Peptic ulcer disease 10. Dementia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity is assessed during the first 24 hours post-surgery using the visual analogue scale (VAS) (at the 10th minute, 1, 2, 6, 12, and 24 hours postoperatively). | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessed during the first 24 hours post-surgery (at the 10th minute, 1, 2, 6, 12, and 24 hours postoperatively): 1. Morphine consumption 2. Morphine-related side effects 3. Ramsay Sedation Scale (RSS) 4. Blood pressure 5. Heart/respiratory rate | — |
Countries
Turkey
Outcome results
None listed