Rotavirus Group A (RVA) diarrhoea Infections and Infestations
Conditions
Interventions
This study involves the collection of stool samples from children (0-5 years) presenting with diarrhoea in Ile-Ife in the southwestern part of Nigeria. Controls (children without diarrhoea for the pas
Sponsors
Obafemi Awolowo University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Cases: 1. Children (aged 0 to 60 months) 2. Acute diarrheal episode (diarrhoea will be defined as three or more loose stools in the last 24 hours with or without other symptoms such as fever, vomiting or dehydration and the onset must be within the last 7 days) Controls: 1. Healthy children coming to the same hospital/health centre for routine immunization and not presenting with gastroenteritis symptoms for the past 14 days
Exclusion criteria
Exclusion criteria: Cases: 1. Children who do not have diarrhoea 2. Children older than 5 years 3. Parents or guardians do not give formal consent to participate in the study Controls: 1. Sick children 2. Children older than 5 years 3. Parents or guardians do not give formal consent to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RVA detected using ELISA, PCR and the developed nanoparticle-based RVA kit at the end of 1-year sample collection | — |
Secondary
| Measure | Time frame |
|---|---|
| Sociodemographic, environmental/clinical/risk factors associated with diarrhoea assessed using a structured questionnaire during the 1-year study period | — |
Countries
Nigeria
Outcome results
None listed