Effect of a postoperative exercise program on arteriovenous fistula maturation

Effect of a postoperative exercise program on arteriovenous fistula maturation: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN15802482

Enrollment

Registered

2015-03-29

Start date

2013-06-01

Completion date

Unknown

Last updated

2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arteriovenous fistula is a surgically connection between an artery and a vein, that is created as a method for achieving vascular access in chronic hemodialysis patients. Surgery

Interventions

After arteriovenous fistula creation, all patients will be randomized to an exercise or control group. Patients in the exercise group will be asked to follow a previously designed controlled exercise

only the nurse instructing patients to follow the exercise program and the patients themselves will know the results of randomization).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients with chronic kidney diseases stages 5 (pre-dialysis) and 5D (hemodialysis) who visited in our center and are candidates for the creation of native AVF (arteriovenous fistula) in the upper extremity are invited to participate in this study. The inclusion criteria consisted of: 1. Ambulatory status 2. The ability to understand and perform the exercise program and attend a follow-up visit 3. Acceptance to participate 4. Provision of signed informed consent after receiving full information on the program

Exclusion criteria

Exclusion criteria: 1. Patients with previous dysfunctioning AVF in the same arm (AVF repairs) 2. Prosthetic accesses 3. Known arterial or venous diseases in the same arm

Design outcomes

Primary

Measure	Time frame
Primary outcome is arteriovenous fistula maturation one month after fistula creation (yes/no, and % of arteriovenous fistula). It is measured by clinical and ultrasonographic methods: 1. Clinical maturation is defined, after physical examination by a dedicated nurse and medical specialists, as an easily palpable vein, with a straight-superficial segment, length more than 10 cm, sufficient diameter and good palpable thrill. 2. Ultrasonographic maturation is defined, after ultrasound examination, as a draining vein diameter = 5 mm, skin-vein distance = 6 mm and brachial blood flow rate (BFR) = 500 mL/min.	—

Measure

Time frame

Primary outcome is arteriovenous fistula maturation one month after fistula creation (yes/no, and % of arteriovenous fistula). It is measured by clinical and ultrasonographic methods: 1. Clinical maturation is defined, after physical examination by a dedicated nurse and medical specialists, as an easily palpable vein, with a straight-superficial segment, length more than 10 cm, sufficient diameter and good palpable thrill. 2. Ultrasonographic maturation is defined, after ultrasound examination, as a draining vein diameter = 5 mm, skin-vein distance = 6 mm and brachial blood flow rate (BFR) = 500 mL/min.

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Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026