Semen quality improvement of patients with azoospermia and low sperm count Urological and Genital Diseases Male infertility
Conditions
Interventions
A mixture of multi-active natural products, antioxidants, anti-inflammatory ingredients, and high-quality honey, called the 'Manfort supplement' will be used in this study.
Male patie
Sponsors
Egypt Innovate for Development and Training Foundation
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Aged 36 to 46 years 2. Married 3. Low sperm total count: sperm concentration ?17 million after two semen analysis tests 4. Azoospermia patients show spermatogonia cells in each semen analysis 5. Body weight ranging from 65 to 95 kg 6. All patients living in a geographic area where follow-up can be accomplished
Exclusion criteria
Exclusion criteria: 1. Patients suffering from other diseases such as varicocele were exempted from this study 2. Patients characterized with Sertoli cell only syndrome or absence of spermatogonia 3. Patients who take medications are exempted from this study to prevent semen analysis disturbance 4. Signs of infection or fever
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measured at baseline (pre-treatment) and 4 months (post-treatment) from two semen specimens collected by masturbation: 1. Semen volume (by weight [g]) 2. Sperm concentration (hemacytometer) 3. Sperm motility (phase-contrast microscope) 4. Semen WBCs (high power field (HPF) using the hemacytometer slide and light microscope) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Liver function measured using spectrophotometric assay of alanine transaminase (ALT) and aspartate aminotransferase (AST) | — |
Countries
Egypt
Contacts
Public ContactAhmed M. Abu-Dief
Outcome results
None listed