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Preventive intervention of mild cognitive impairment in Anhui, China

Risk stratification and hierarchical intervention strategy for mild cognitive impairment among older community dwellers

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN15775827
Enrollment
88
Registered
2022-09-21
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment (MCI) Mental and Behavioural Disorders Mild cognitive disorder

Interventions

The intervention was divided into two stages. In the first stage, the 24-weeks of intervention were given to the intervention group (community A), and for the control group (community B) only natural
however, the same 24-weeks preventive intervention started for community B. Interventions focused on nine risk factors: social isolation, cognitive reserve, drinking, smoking, hyperte

Sponsors

National Natural Science Foundation of China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 55-75 years, male or female 2. Owning a smartphone, have Instant Messenger (e.g., WeChat), and can use it proficiently 3. Is a permanent resident of the community and has no plan to leave the community for a long-term residence elsewhere within 1 year 4. Normal cognitive function (MMSE score of 24 or higher) 5. Be aware of the purpose of this study and willing to participate (sign informed consent)

Exclusion criteria

Exclusion criteria: Older adults with MCI or AD at baseline

Design outcomes

Primary

MeasureTime frame
The change in the total risk score of each individual was used as the main observation index at baseline and at 8, 16, and 24 weeks

Secondary

MeasureTime frame
1. Somatic function measured using the results evaluated by neurology professionals at baseline and at 8, 16, and 24 weeks 2. Cognitive function measured using the Mini-Mental State Examination (MMSE) at baseline and at 8, 16, and 24 weeks 3. Activities of daily living measured using the activities of daily living (ADL) at baseline and at 8, 16, and 24 weeks 4. Psychological status measured using the 9-item Patient Health Questionnaire (PHQ-9) at baseline and at 8, 16, and 24 weeks 5. Quality of life measured using the EQ-5D at baseline and at 8, 16, and 24 weeks

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026