Healthy volunteers Nutritional, Metabolic, Endocrine
Conditions
Interventions
After consent, we will ask participants to fast for 24 hours. During this period, drinking water is allowed and encouraged. Afterwards, we will measure baseline blood ketone levels and perform a Phosp
Sponsors
TdeltaS Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Fluent in English with no communication impairments 2. Willing and able to give informed consent for participation in the study 3. Aged 18-70 years (inclusive) 4. No known medical diagnosis 5. No prescribed medication 6. In the Investigator’s opinion, able and willing to comply with all study requirements
Exclusion criteria
Exclusion criteria: 1. Contraindication for undergoing Magnetic Resonance Imaging (MRI), such as metallic implanted devices, shrapnel or claustrophobia 2. Pregnant, lactating or planning to get pregnant 3. Any other significant disease or disorder which, in the opinion of the investigator, may either put the participants at risk because of participation in the study, or may influence the result of the experiment, or the participant’s ability to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac phosphocreatine/ATP (PCr/ATP) ratio assessed using 31P MRS scan after 24 h fasting and 30 minutes after drinking the ketone monester solution | — |
Countries
United Kingdom
Outcome results
None listed