Screening for gestational diabetes: a randomised clinical trial of two universal methods

Screening for gestational diabetes: a randomised clinical trial comparing the glucose challenge test and the oral glucose tolerance test

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN15700608

Enrollment

600

Registered

2019-10-07

Start date

2013-10-02

Completion date

Unknown

Last updated

2019-10-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes Pregnancy and Childbirth Diabetes mellitus arising in pregnancy

Interventions

The interventions involved in this trial are the two methods of screening for gestational diabetes: 1. The oral glucose tolerance test involves an overnight fast of at least 12 hours,

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: All pregnant women aged 18-45

Exclusion criteria

Exclusion criteria: 1. Previous diagnosis of diabetes 2. Use of insulin 3. HbA1C>6.5% 4. Inability to give informed consent

Design outcomes

Primary

Measure	Time frame
Maternal blood glycated haemoglobin level (HbA1c) at 16 and 36 weeks gestation	—

Secondary

Measure	Time frame
1. Maternal quality of life measured using PES scale, DASS, PSSS, EQ5D 2. Cost (attendance for GDM screening, attendance for prenatal visits, number of prenatal visits) 3. Fetal and neonatal parameters (large-for-gestational-age, birth weight> 4 kg, shoulder dystocia, bone fracture, nerve palsy, stillbirth, perinatal death, hypoglycaemia, weight, jaundice, admission to the special care baby unit) 4. Maternal and delivery parameters (gestational hypertension, pre-eclampsia, eclampsia, gestational diabetes, hypoglycaemia, HbA1c >5.6%, receipt of nutritional counselling, use of glucose-lowering therapies, blood pressure, weight gain, induction of labour, caesarean delivery)	—

Measure

Time frame

1. Maternal quality of life measured using PES scale, DASS, PSSS, EQ5D 2. Cost (attendance for GDM screening, attendance for prenatal visits, number of prenatal visits) 3. Fetal and neonatal parameters (large-for-gestational-age, birth weight> 4 kg, shoulder dystocia, bone fracture, nerve palsy, stillbirth, perinatal death, hypoglycaemia, weight, jaundice, admission to the special care baby unit) 4. Maternal and delivery parameters (gestational hypertension, pre-eclampsia, eclampsia, gestational diabetes, hypoglycaemia, HbA1c >5.6%, receipt of nutritional counselling, use of glucose-lowering therapies, blood pressure, weight gain, induction of labour, caesarean delivery)

—

Countries

Ireland

Contacts

Public ContactTomas Ahern

hamillma@tcd.ie+353 (0)872079003

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026