A research database collecting long-term behavioural data directly from participants, and health data from medical records to create a bank of data pertaining to people who have quit smoking, both with and without switching to e-cigarettes

A long-term health data repository of people who have quit smoking with and without using e-cigarettes

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN15698754

Enrollment

500

Registered

2022-08-31

Start date

2021-09-01

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E-cigarette use Other

Interventions

The Registry is an open-ended, prospective observational research study (with no experimental procedure) to capture the long-term health effects of EC use. The design of the study is data linkage of i

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Is 16+ years of age 2. Has a previous tobacco quit attempt 3. Consents to data linkage 4. Willing to provide annual follow-up data through direct methods (questionnaires) and indirect methods (through their health records) 5. Resides in England or Wales

Exclusion criteria

Exclusion criteria: 1. Unwilling or unable to give consent 2. Cannot communicate (written and spoken) in English

Design outcomes

Primary

Measure	Time frame
1. Demand for Registry service measured using targeted surveys during scoping phase (pre-recruitment) 2. The availability and challenges of completing linkage for non-cancers/death particularly in primary care, assessed using quantitative and qualitative analysis at 6 monthly intervals until study end 3. Mortality and cancer incidence data collected from NHS Digital for all participants recruited at the time of application 4. Smoking/vaping status collected using automated participant surveys annually for 1 year	—

Measure

Time frame

1. Demand for Registry service measured using targeted surveys during scoping phase (pre-recruitment) 2. The availability and challenges of completing linkage for non-cancers/death particularly in primary care, assessed using quantitative and qualitative analysis at 6 monthly intervals until study end 3. Mortality and cancer incidence data collected from NHS Digital for all participants recruited at the time of application 4. Smoking/vaping status collected using automated participant surveys annually for 1 year

—

Secondary

Measure	Time frame
1. Recruitment rate recorded as the number of eligible participants who consent to participate in the study at month 17 (recruitment end) 2. Retention rate assessed using the number of participants who consent to participate who remain in the study until the end of follow-up at month 17 (recruitment end)	—

Countries

England, United Kingdom, Wales

Contacts

Public ContactGeorgia Mannion-Krase

georgia.mannion-krase@kcl.ac.uk+44 (0)20 7836 5454

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: May 1, 2026