Can magnetic resonance imaging give more information than computed tomography in the assessment of acute pancreatitis?

Computed tomography and magnetic resonance imaging in the assessment of acute pancreatitis, a comparative study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN15672917

Enrollment

Registered

2021-11-25

Start date

2020-12-02

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pancreatitis Digestive System Acute pancreatitis

Interventions

Each patient will undergo a CT examination with intravenously injected contrast medium administration within 48-72 hours of admission to assess the severity of AP. Patients who signed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with AP in the visceral surgery department at the Lausanne University Hospital (CHUV), Switzerland, during the period between December 2020 and November 2021. According to the guidelines, AP is defined as two or more of the following characteristics: abdominal pain, and serum amylase or lipase levels three or more times the upper limit of normal (>210 U/L and >180 U/L, respectively). 2. Patients undergoing a contrast-enhanced CT during their hospital stay about 48-72 hours after admission

Exclusion criteria

Exclusion criteria: 1. Intubation and/or ventilation 2. Renal failure with estimated glomerular filtration rate (GFR) less than 30 ml/min/1.73 m²) 3. History of allergic reactions to any contrast media 4. Proven or suspected pregnancy 5. Age under 18 years 6. General exclusion criteria for MRI: 6.1. Patients with non-MRI compatible metallic or electronic implants, devices or metallic foreign bodies (shrapnel, cochlea implants, neurostimulator, or other non-MRI compatible implants) 6.2. Non-MRI compatible cardiac pacemaker 7. Previous diagnosis of chronic pancreatitis 8. Inability to cooperate because of claustrophobia 9. Inability to cognitively and/or linguistically understand the patient consent sheet 10. Patients with missing clinical or radiological data

Design outcomes

Primary

Measure	Time frame
AP severity graded according to the severity index on CT and MRI within 48-72 hours of admission	—

Secondary

Measure	Time frame
AP severity assessed clinically using the Ranson score, laboratory values and the further clinical evolution of pancreatitis during hospitalisation	—

Countries

Switzerland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026