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Optical Tissue Stylet - study into vascular access in humans

Optical Tissue Stylet - randomized controlled trial into vascular access in humans

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN15608308
Enrollment
20
Registered
2015-02-25
Start date
2011-06-30
Completion date
Unknown
Last updated
2023-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Regional anesthesia Not Applicable

Interventions

Volunteers will be recruited via flyers and posters. The study will encompass one visit per subject. Subjects will be randomly divided into two groups. Per group, a different needle endpoint has been

Sponsors

Philips Healthcare
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. More than 18 years old 2. Healthy (category 1 of the ASA physical status classification system)

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Photodynamic therapy 3. Inability to give informed consent 4. Category 2 and higher of the ASA physical status classification system

Design outcomes

Primary

MeasureTime frame
The primary objective of the trial is to investigate if the optical tissue stylet technology can reliably discriminate intra-vascular (venous) from non-vascular punctures. Diffuse reflectance spectra will be acquired for these two situations, with custom-made needle stylets that contain optical fibers.

Secondary

MeasureTime frame
1. Successfully acquired diffuse reflectance spectra obtained in subcutaneous fat surrounding the veins in the anterior forearm, and spectra obtained with the needle tip inside veins in the anterior forearm 2. Recordings of positive/negative aspiration results for the locations where the diffuse reflectance spectra have been taken 3. Confirmation images by ultrasound, at the locations where the diffuse reflectance spectra have been collected 4. Estimates of the diameters of the punctured veins, based on information from ultrasound imaging 5. Percentages correctly identified positive and negative vessel punctures, where the identification is provided by an observer who only has access to the diffuse reflectance spectra, and is blinded to all other aspects of the procedures

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026