A feasibility trial of community-based pulmonary rehabilitation for adults with chronic obstructive pulmonary disease (COPD) in India

A single-arm feasibility trial of community-based pulmonary rehabilitation for adults with COPD in the slum areas of Jodhpur, Rajasthan

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN15546359

Enrollment

Registered

2021-10-05

Start date

2022-01-24

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease (COPD) Respiratory Chronic obstructive pulmonary disease

Interventions

In addition to usual care, participants in the intervention arm will receive pulmonary rehabilitation (PR). PR will comprise the core elements of an evidence-based rehabilitation, a programme of exerc

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years 2. Spirometry confirmed diagnosis of chronic obstructive pulmonary disease (COPD) 3. Functional limitation due to breathlessness reaching a score of =2 on the Medical Research Council (MRC) dyspnea scale

Exclusion criteria

Exclusion criteria: 1. Significant comorbidities such as cardiovascular, neurological, locomotor difficulties that preclude exercise, cognitive, malignant disease, or any other condition that would compromise participation in the rehabilitation programme 2. COVID-19 RT-PCR positive result within 3 days of assessment 3. Unable to provide informed consent.

Design outcomes

Primary

Measure	Time frame
Feasibility and the acceptability of the PR intervention measured using semi-structured in-depth interviews with participants at 6 weeks	—

Secondary

Measure	Time frame
1. Lung function measured using the following at baseline and 6 weeks: 1.1. Spirometry to calculate pre- and post-bronchodilator forced expiratory volume in one second [FEV1], forced vital capacity [FVC], and FEV1/FVC ratio 1.2. Questionnaires to calculate smoking status and number of COPD exacerbations in the last year 2. Health status measured using the following at baseline and 6 weeks: 2.1. Participant perceived respiratory disability due to dyspnea using the Medical Research Council (MRC) dyspnea scale 2.2. Health-related quality of life using the chronic obstructive pulmonary disease assessment test (CAT) 2.3. Economic impact using the Work Productivity and Activity Impairment (WPAI) questionnaire 2.4. Emotional health using the Hospital Anxiety and Depression Scale (HADS) 3. Physical fitness measured using the following at baseline and 6 weeks: 3.1. Exercise capacity using the incremental shuttle walk test (ISWT) and the endurance shuttle walking test (ESWT) 3.2. Lower extremity muscular strength using a five-repetition sit-to-stand test (5XSST)	—

Measure

Time frame

1. Lung function measured using the following at baseline and 6 weeks: 1.1. Spirometry to calculate pre- and post-bronchodilator forced expiratory volume in one second [FEV1], forced vital capacity [FVC], and FEV1/FVC ratio 1.2. Questionnaires to calculate smoking status and number of COPD exacerbations in the last year 2. Health status measured using the following at baseline and 6 weeks: 2.1. Participant perceived respiratory disability due to dyspnea using the Medical Research Council (MRC) dyspnea scale 2.2. Health-related quality of life using the chronic obstructive pulmonary disease assessment test (CAT) 2.3. Economic impact using the Work Productivity and Activity Impairment (WPAI) questionnaire 2.4. Emotional health using the Hospital Anxiety and Depression Scale (HADS) 3. Physical fitness measured using the following at baseline and 6 weeks: 3.1. Exercise capacity using the incremental shuttle walk test (ISWT) and the endurance shuttle walking test (ESWT) 3.2. Lower extremity muscular strength using a five-repetition sit-to-stand test (5XSST)

—

Countries

India

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026