Urine and blood biomarkers after consumption of dietary polyphenols Nutritional, Metabolic, Endocrine
Conditions
Interventions
Twenty subjects were randomized into either the coffee group or the green tea group (10 for each group). They ingested a test beverage including either 390 mg chlorogenic acids for the coffee group or
Sponsors
Kao Corporation (Japan)
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Healthy volunteers aged 20 to 59 years 2. Male 3. Normal weight or overweight (body mass index 18.5-29.9 kg/m2)
Exclusion criteria
Exclusion criteria: 1. Caffeine intoxication 2. Food allergy 3. Intake of catechins or chlorogenic acid supplements 4. Serious illness (such as heart disease, kidney disease, diabetes and so on)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolomic profiles of urine and blood which associate with indirect calorimetry; Timepoints: baseline (before intervention period), after 4-week intervention period, fasting and postprandial states | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolomic profiles of urine and blood which associate with the polyphenol intake; Timepoints: baseline (before intervention period), after 4-week intervention period, fasting and postprandial states | — |
Countries
Japan
Outcome results
None listed