Diagnosis of osteomyelitis (Bone/joint infection) in children aged 0-15 years Musculoskeletal Diseases
Conditions
Interventions
1. Learn from children who have previously been suspected to have bone and joint infection.
We will look at past records from at least 30 hospitals in the UK. These will tell us which tests were perfo
Sponsors
University of Oxford
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 12/07/2024: 1. The child is aged between 0-15 years. 2. BJI is part of the differential diagnosis, even remotely, and even if the treating clinician believes BJI can be ruled out on the basis of the history and examination alone. 3. The duration of symptoms is less than 2 weeks at the time of attendance to acute healthcare. 4. Symptoms affecting the appendicular skeleton only. _____ Previous inclusion criteria: 1. The child is aged between 0-15 years. 2. The treating clinician is suspicious of a diagnosis of bone and/or joint infection. 3. The duration of symptoms is less than 2 weeks at the time of attendance to acute healthcare.
Exclusion criteria
Exclusion criteria: Current exclusion criteria as of 12/07/2024: 1. There is evidence that the patient and/or parent/guardian would be unable to adhere to study procedures or complete follow-up, such as developmental delay or a developmental abnormality. 2. Limited comprehension by the parent guardian of the English language. This will be assessed by the recruiting team at participating sites. 3. Suspected infections affecting the axial skeleton (skull spine, or ribs). 4. Traumatic aetiology of symptoms _____ Previous exclusion criteria: 1. There is evidence that the patient and/or parent/guardian would be unable to adhere to study procedures or complete follow-up, such as developmental delay or a developmental abnormality. 2. Limited comprehension by the parent guardian of the English language. This will be assessed by the recruiting team at participating sites.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence or absence of proven BJI, which includes osteomyelitis and/or septic arthritis measured using patient records measured at a single time point | — |
Secondary
| Measure | Time frame |
|---|---|
| Experience through semi-structured qualitative interviews with children and parents and focus groups with health professionals measured at a single time point | — |
Countries
England, Northern Ireland, Scotland, United Kingdom, Wales
Contacts
Public ContactDebbie Jewell
Outcome results
None listed