Bowel/colorectal cancer Cancer
Conditions
Interventions
The CADDIE system will be deployed to collect video and histopathology data from patients randomised to high-definition white light colonoscopy with or without Indigo Carmine dye spray and with AI (co
Sponsors
Cardiff University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: In the participating FORE AI sites, all CONSCOP2 (https://www.isrctn.com/ISRCTN98539180) participants will be approached for additional optional consent to participate in the FORE-AI sub-study via the CONSCOP2 main PIS/ICF.
Exclusion criteria
Exclusion criteria: 1. Previous resectional colorectal surgery (as this would influence both study methods and outcomes depending on the length of residual colon in the individual) 2. Any participants not deemed fit for colonoscopy on the screening program or undergoing alternative investigation such as CT pneumocolon or minimal prep CT scan as their index procedure instead. 3. Known allergy to food colouring agent (as the Indigo Carmine dye is a safe food colouring agent but extremely rarely there may be individuals with a specific allergic response to this in the past). 4. Previous inclusion in trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection and diagnosis of polyps using a video of the procedure will be compared between the AI software and the colonoscopists to assess the accuracy of the AI. | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
England, United Kingdom, Wales
Contacts
Public ContactGeorgina Gardner
Outcome results
None listed