Chronic periodontitis Digestive System Chronic periodontitis
Conditions
Interventions
Participants were randomised into a split-mouth design, with allocation of the side to be treated (left or right) performed by drawing lots before the initial periodontal examination.
Clinical and mi
Sponsors
Medical University of Vienna
Eligibility
Inclusion criteria
Inclusion criteria: 1. Presence of moderate to severe periodontitis 2. Aged 35 years or older 3. Probing depths > 5 mm in at least one site in each quadrant 4. Radiologically detectable alveolar bone loss in all quadrants 5. Good general health
Exclusion criteria
Exclusion criteria: 1. Pregnant 2. Systemic or local antimicrobial treatment in the preceding 6 months 3. Periodontal treatment in the preceding 6 months 4. The presence of an infectious disease, chronic pulmonary disease, cancer or diabetes and other apparent oral infections 5. Intake of immunosuppressive medication or immunodeficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding on probing, assessed during probing with a calibrated standard probe at the initial examination (baseline) and 12 weeks after the last treatment (re-evaluation) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Oral hygiene, assessed using The Approximal-Plaque-Index (API) and the Papillary Bleeding Index (PBI) at the initial examination (baseline), at debridement and 12 weeks after the last treatment (re-evaluation) 2. Clinical attachment level, measured to the nearest millimeter using a calibrated standard probe at baseline and re-evaluation 3. Periodontal pocket depth, measured to the nearest millimeter using a calibrated standard probe at baseline and re-evaluation | — |
Countries
Austria
Outcome results
None listed