Influence of respiratory efforts on b2-agonist induced bronchodilation in mechanically ventilated COPD patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN15368477

Enrollment

Registered

2005-07-20

Start date

2003-03-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute exacerbation of chronic obstructive pulmonary disease Respiratory Chronic obstructive pulmonary disease (COPD)

Interventions

All patients were intubated with an endotracheal tube 8-9 mm in internal diameter, sedated (propofol and remifentanyl) and initially ventilated (for 24 to 36 hours) on volume-controlled (VC) mode usin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with chronic obstructive pulmonary disease (COPD), requiring endotracheal intubation and mechanical ventilation to manage acute respiratory failure due to an acute exacerbation of chronic airflow obstruction, were studied. All patients had a previous diagnosis of COPD and met established criteria for this diagnosis.

Exclusion criteria

Exclusion criteria: Hemodynamically unstable

Design outcomes

Primary

Measure	Time frame
Respiratory system mechanics (Resistance)	—

Secondary

Measure	Time frame
Heart rate, arterial blood gasses	—

Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026