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Invisible funnel chest

Thoracic constriction without evidence of the typical funnel-shaped depression – the invisible pectus excavatum

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN15355937
Enrollment
100
Registered
2022-06-21
Start date
2020-02-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with cardiac symptoms and elevated Haller-Index in cardiac magnetic resonance imaging Circulatory System

Interventions

Biventricular global strain analysis is assessed using cardiac magnetic resonance feature tracking (CMR-FT). ECG and in some cases Holter recordings are performed to detect rhythm events. Cardiac symp

Sponsors

University Medical Centre Mannheim
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who undergo cardiac magnetic resonance imaging for further evaluation of the heart due to cardiac symptoms (such as palpitations, dyspnea, atypical chest pain, syncope) and unobtrusive echocardiography, with relative thoracic constriction due to an elevated Haller-Index.

Exclusion criteria

Exclusion criteria: 1. Inability to give informed consent 2. Definitive cardiac diagnosis

Design outcomes

Primary

MeasureTime frame
Determination of the Haller index, defined as the ratio of the transverse thoracic diameter divided by the frontodorsal diameter of the chest, by analyzing magnetic resonance imaging (MRI) data, measured at the time of study inclusion. For this, only two distances are measured on the MRI image and related to each other.

Secondary

MeasureTime frame
1. Correction index, measured by cardiac magnetic resonance imaging (CMR) at the time of study inclusion. The correction index is defined as the minimum distance between the posterior sternum and anterior spine and the maximum distance between the anterior spine and most anterior portion of the chest. The difference between the two is divided by the latter (×100) to give the percentage of chest depth the defect represents. 2. Depression index, measured by CMR at the time of study inclusion. The depression index is derived from the absolute measurement of sternal depression using the transverse vertebral body diameter as a surrogate for height. 3. Intracardiac angles, measured by CMR at the time of study inclusion. Intracardiac angles were determined to describe the deviation of the heart axis by measuring three different intracardiac angles, including the angle between the perpendicular of the thorax and the apex of the right ventricular/insertion of the two ventricles/apex of the left ventricle.

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 10, 2026