Endothelial dysfunction in patients with diabetes and pre-diabetes with normal coronary arteries Circulatory System
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients evaluated in the Cardiology outpatient clinic who were found to have normal coronary arteries on coronary angiography 2. Aged 21-80 years
Exclusion criteria
Exclusion criteria: 1. A history of previous percutaneous coronary intervention 2. Atrial fibrillation 3. Heart failure 4. More than mild valvular regurgitation 5. Valvular stenosis 6. Uncontrolled hypertension (systolic blood pressure = 160 mmHg and diastolic blood pressure =90 mmHg in the last 6 weeks) 7. Cardiomyopathy 8. Chronic kidney or liver disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Flow-mediated dilation is measured by an ultrasound system equipped with a 5-10 MHz linear array transducer from the brachial artery at baseline and after vasodilation, using an ultrasound, taken once per patient | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
Türkiye