Lung cancer Cancer
Conditions
Interventions
Arm 1: Interventional Group (Multimodal Prehabilitation)
Participants in this arm receive a comprehensive, supervised multimodal prehabilitation program lasting for a total duration of 2–4 weeks prio
Sponsors
Poznan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Confirmed Diagnosis: Histologically or cytologically confirmed primary lung cancer (e.g., Non-Small Cell Lung Cancer). 2. Age: Patients aged between 18 and 80 years (inclusive) at the time of signing the informed consent. 3. Treatment Plan: Patients qualified and scheduled for elective surgical resection via lobectomy or Video-Assisted Thoracoscopic Surgery (VATS). 4. Clinical Status: Patients cleared by a multidisciplinary team (MDT) or surgeon as fit for surgery, with preserved consciousness and the ability to maintain logical verbal contact. 5. Informed Consent: Ability to provide voluntary, written informed consent to participate in the study and comply with the prehabilitation protocol.
Exclusion criteria
Exclusion criteria: 1. Contraindicating comorbidities: Presence of severe comorbidities that prevent the safe performance of endurance training or the 6-minute walk test (6MWT), including but not limited to severe heart failure (NYHA III/IV) or uncontrolled hypertension. 2. Cardiovascular instability: Recent myocardial infarction (within the last 6 months) or unstable angina that contraindicates physical exertion. 3. Locomotor and neurological disabilities: Severe orthopaedic, musculoskeletal, or neurological impairments that prevent the participant from completing the exercise protocol or functional assessments. 4. Cognitive and communication barriers: Patients in a state of minimal consciousness, or those with cognitive impairments (e.g., dementia) that prevent logical verbal contact or the ability to follow study instructions. 5. Refusal of consent: Patients who do not provide voluntary, written informed consent to participate in the study. 6. Urgent surgical requirement: Patients requiring emergency or urgent surgery within a timeframe that does not allow for completion of the prehabilitation protocol. 7. Advanced malignancy: Presence of concurrent advanced cancers or metastatic disease (Stage IV) that would significantly limit physical performance or life expectancy. 8. Severe respiratory failure: Baseline requirement for continuous long-term oxygen therapy (LTOT) that prevents participation in the training program. 9. Concurrent trial participation: Enrolment in another interventional clinical trial that could interfere with the study’s primary outcomes or parameters.
Countries
Poland
Contacts
Public ContactKrystian Mania
Outcome results
None listed