Type 2 diabetes mellitus Nutritional, Metabolic, Endocrine Type 2 diabetes mellitus
Conditions
Interventions
Interventions as of 11/10/2018:
Some changes were made to the study, largely to do with challenges in recruitment. The methods for the study, in the preliminary version of the journal article, are bel
Sponsors
University College Dublin
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Confirmed diagnosis of T2DM > 6 months 2. Sedentary – not currently participating in any physical activity (in line with results of the Active Australia Survey) 3. Treated with oral hypoglycaemic agents and diet alone and not with insulin 4. Aged 40-65 years 5. Male and Female 6. Hba1c 7-10%
Exclusion criteria
Exclusion criteria: 1. Any mental, neurological, cardiovascular, musculoskeletal or orthopaedic deficiency contra-indicating regular training and/or muscular testing or making it impossible or preventing knowing consent to the study 2. Infectious or inflammatory evolving affection 3. Evidence of chronic renal failure or liver disease 4. Severe proliferative diabetic retinopathy 5. Currently or recently pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Adherence to the exercise prescription is assessed using logbooks in the exercise alone group and using logbooks and self reported adherence in the mobile phone application in the exercise and coaching app group at 16 weeks (exercise groups only) 2. Physical activity levels are measured using the Active Australia Survey at baseline and 16 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures as of 09/10/2018: 1. Weight is measured using a weighing scales at baseline and 16 weeks 2. BMI is calculated using height and weight measurements taken at baseline and 16 weeks 3. Neuromuscular function using electromyography (EMG) during isometric and isokinetic dynamometry at different speeds at baseline and 16 weeks 4. Functional fitness is measured using the 6 minute walk test at baseline and 16 weeks 5. Grip strength is measured using a hand grip dynamometer at baseline and 16 weeks 6. Lipid profile is measured using blood testing at baseline and 16 weeks 7. Glycated haemoglobin is measured using blood samples collected at baseline and 16 weeks Exit interviews were conducted to allow for qualitative analysis of the interventions. Previous secondary outcome measures: 1. Weight is measured using a weighing scales at baseline and 16 weeks 2. BMI is calculated using height and weight measurements taken at baseline and 16 weeks 3. Blood pressure is measured using a sphygmomanometer at baseline and 16 weeks 4. Neuromuscular function using electromyography (EMG) during isometric and isokinetic dynamometry at different speeds at baseline and 16 weeks 5. Functional fitness is measured using the 6 minute walk test at baseline and 16 weeks 6. Grip strength is measured using a hand grip dynamometer at baseline and 16 weeks 7. Lipid profile is measured using blood testing at baseline and 16 weeks 8. Glycated haemoglobin is measured using blood samples collected at baseline and 16 weeks | — |
Countries
Ireland
Outcome results
None listed