How much volume of a local anesthetic is necessary to accomplish a nervus saphenous block

Minimum local anaesthetic volumes for saphenous nerve block: A dose-finding study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN15319297

Enrollment

Registered

2016-01-25

Start date

2015-02-12

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Saphenous nerve block Not Applicable Saphenous nerve block

Interventions

Patients will receive a distal ultrasound-guided saphenous nerve block. Briefly, the ultrasound probe will be used to locate the femoral artery over the medial aspect of the thigh. The artery will be

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 65 years 2. ASA physical status I-II (healthy)

Exclusion criteria

Exclusion criteria: 1. Allergy against local anesthetics 2. Contraindication for saphenous nerve block (infection at injection site, local pathology) 3. Ingestion of any pain medication within the past 24 hours 4. Pregnancy or breastfeeding

Design outcomes

Primary

Measure	Time frame
Effective volume to produce complete neural blockade is determined using a pinprick in the sensory area of the saphenous nerve to provoke a dichotomous yes/no answer, 30 minutes after block.	—

Secondary

Measure	Time frame
1. Influence of the volume on duration of sensory blockade is measured using pinpricks at the apex of the patella, medial aspect of the medial facet of the tibial plateau and the skin over the medial ankle at 2, 4, 6, 8, 10, 15, 20, 25, and 30 minutes, and then every 15 minutes until block resolution 2. Extent of potential motor blockade is measured using the MRC-scale 20 minutes after block onset 3. The maximum spread of sensory block on the skin surface is measured using pinpricks to establish the edge of the anaesthetised area 20 minutes after block onset	—

Measure

Time frame

1. Influence of the volume on duration of sensory blockade is measured using pinpricks at the apex of the patella, medial aspect of the medial facet of the tibial plateau and the skin over the medial ankle at 2, 4, 6, 8, 10, 15, 20, 25, and 30 minutes, and then every 15 minutes until block resolution 2. Extent of potential motor blockade is measured using the MRC-scale 20 minutes after block onset 3. The maximum spread of sensory block on the skin surface is measured using pinpricks to establish the edge of the anaesthetised area 20 minutes after block onset

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Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026