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Levamisole hydrochloride as adjunctive therapy in falciparum malaria

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN15314870
Enrollment
40
Registered
2005-10-14
Start date
2003-10-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Falciparum malaria Infections and Infestations Malaria

Interventions

Patients admitted to Mae Sot Hospital with uncomplicated falciparum malaria will be randomised to either adjunctive treatment with a single dose of 150 mg oral levamisole hydrochloride, or no adjuncti

Sponsors

University of Oxford (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The patient or attending relative is able and willing to give informed consent - the proposed consent form and information sheets are attached and will be translated into Burmese 2. Uncomplicated falciparum malaria 3. Patients aged 16 to 65 years old, either sex 4. No contraindications to levamisole, quinine or doxycycline therapy, like documented allergies to any of the drugs

Exclusion criteria

Exclusion criteria: 1. Patient or relatives unable or unwilling to give informed consent 2. Previous antimalarial treatment within one week of admission 3. Pregnancy

Design outcomes

Primary

MeasureTime frame
Sequential assessment of peripheral blood parasitaemia and parasite stages.

Secondary

MeasureTime frame
No secondary outcome measures

Countries

Thailand

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026