Comparison of prilocaine and mepivacaine for perianal surgery in an outpatient setting

Comparison of 0.5ml hyperbaric prilocaine 2% versus 0.5ml hyperbaric mepivacaine 4% for low-dose spinal anaesthesia in patients undergoing perianal surgery in an ambulatory setting

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN15303706

Enrollment

160

Registered

2012-07-25

Start date

2011-07-26

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal diseases Digestive System Rectosigmoid junction diseases

Interventions

Participants are randomised (1:1) and assigned to a dose of either 0.5ml of hyperbaric prilocaine 2% or of 0.5ml of hyperbaric mepivacaine 4%. The expansion of sensory and motor blocks are tested. A

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients (male or female) undergoing minor perianal surgery 2. Aged 18 - 80 years 3. American Society of Anesthesiologists (ASA) physical status I-III

Exclusion criteria

Exclusion criteria: 1. Contraindications for spinal anaesthesia 2. Allergy to diclofenac, metamizole, paracetamole, piritramid or one of the local anaesthetics used 3. Patients with language barriers

Design outcomes

Primary

Measure	Time frame
1. Period of time till discharge 2. Occurence of transient neurologic symptoms	—

Secondary

Measure	Time frame
1. Occurence of pain 2. Patient?s satisfaction 3. Expansion of sensory and motor block 4. Time span until patient is able walk and void	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026