Skip to content

Evaluating a novel diagnostic test for the detection of Plasmodium infections at community level in The Gambia and Burkina Faso

Evaluating a novel diagnostic test for the detection of Plasmodium infections at community level in The Gambia and Burkina Faso

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN15263932
Enrollment
1900
Registered
2024-08-15
Start date
2023-11-09
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diagnosis of Plasmodium infection Infections and Infestations

Interventions

Clinical samples will be obtained from participants recruited through community-based cross-sectional surveys. These samples will be tested for Plasmodium infection using Dragonfly, RDT, microscopy, a

Sponsors

MRC Unit The Gambia at LSHTM
Lead Sponsor
Clinical Research Unit Nanoro
Collaborator

Eligibility

Sex/Gender
All
Age
6 Months to 99 Years

Inclusion criteria

Inclusion criteria: 1. >6 months of age 2. Present in the household at the time of the interviews 3. Consent to participate in the study (or consent given by an adult caregiver if <18 years old and assent for children =12 years old)

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

MeasureTime frame
Diagnostic accuracy of Dragonfly in detecting Plasmodium infection at the time of recruitment assessed by comparing Dragonfly results against reference standard (PCR).

Secondary

MeasureTime frame
1. Diagnostic accuracy of RDT in detecting Plasmodium infection at the time of recruitment by comparing RDT results against reference standard (PCR). 2. Diagnostic accuracy of microscopy in detecting Plasmodium infection at the time of recruitment by comparing microscopy results against reference standard (PCR). 3. Ease of use of Dragonfly assessed using qualitative interview guides within 4 weeks after presentation of Dragonfly technology to the potential users. 4. Factors influencing the uptake of community-based interventions such as mass testing and treatment assessed using qualitative interview guides within 6 months after the cross-sectional surveys.

Countries

Burkina Faso, Gambia

Contacts

Public ContactAnnette;Dimbintsoa Erhart;Rakotomalala Robinson

;

annette.erhart@lshtm.ac.uk;Dimbintsoa.Rakotomalala1@lshtm.ac.uk+220 700 9779;+220 72 059 38

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026