Ovarian cancer, other intra-abdominal neoplasms Cancer
Conditions
Interventions
A diagnostic cross-sectional retrospective study is performed in patients with pelvic mass, peritoneal carcinomatosis and/or ascites and initial suspicion of ovarian malignancy. All patients have seru
Sponsors
Hospital de Câncer de Barretos
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients with a pelvic mass, peritoneal carcinomatosis and/or ascites
Exclusion criteria
Exclusion criteria: 1. Previous surgery at another service 2. If the pathology results showed benign lesions 3. If the sample was insufficient for a definitive diagnosis 4. If no biopsy was performed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Receiver operating characteristic (ROC) curves to determine the cut-off values for CA-125/CEA ratio in the participants, comparing ovarian cancer with non-ovarian cancer, gastrointestinal cancer, and colorectal cancer, followed by a performance characteristic test to determine sensitivity, specificity, positive predictive value, accuracy (all ovarian cancer positive cases divided by the participants), type I error, 1, and 2 (the power of the test), positive predictive value, negative predictive value, accuracy (all ovarian cancer positive cases divided by all participants), type I error, 1 minus type II error (the power of the test), positive and negative likelihood ratios with pathology findings as the gold standard (chi-squared test or Fisher's test). Measured at a single timepoint. | — |
Secondary
| Measure | Time frame |
|---|---|
| The same as the primary outcome measure but after propensity score matching analysis (PSM) | — |
Countries
Brazil
Contacts
Public ContactJeferson Zanon
Outcome results
None listed