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Implication of gender and sex on the combined effects of physical activity and air pollution exposure in patients with and without chronic respiratory disease

Implication of gender and sex on the combined effects of physical activity and air pollution exposure in patients with and without chronic respiratory disease (INCLUDE)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN15207611
Enrollment
180
Registered
2026-01-14
Start date
2026-01-31
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The study investigates older adults with and without chronic respiratory diseases (CRD), specifically chronic obstructive pulmonary disease (COPD) and asthma, to assess the combined effects of physical activity and air pollution exposure. Respiratory

Interventions

Participants will complete a series of four supervised outdoor walking circuits under differing environmental exposure and physical activity intensity conditions. Each participant will act as their ow

Sponsors

Swiss National Science Foundation
Lead Sponsor
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
Collaborator
Societat Catalana de Pneumologia (SOCAP)
Collaborator

Eligibility

Sex/Gender
All
Age
60 Years to 100 Years

Inclusion criteria

Inclusion criteria: 60 years and older

Exclusion criteria

Exclusion criteria: 1. Presence of any alteration that may limit mobility or physical performance. 2. Inability to follow the study procedures (e.g. due to language barriers, psychological disorders, dementia, etc.) 3. Inability to provide informed consent Participants without chronic respiratory disease: 1. Diagnosis or pharmacological treatment for any chronic respiratory disease and/or presence of respiratory symptoms (chronic cough, wheezing, breathlessness at rest or at low intensity exercise, etc). 2. Exercise-induced asthma Participants with COPD: 1. Having undergone major lung surgery (e.g. lung transplant) or lung volume reduction within 6 months before inclusion 2. Primary respiratory diseases other than COPD 3. Substantial limitations in mobility due to factors other than COPD 4. Lung volume reduction within 6 months before inclusion 5. Diagnosis of asthma Participants with asthma 1. Primary respiratory diseases other than asthma 2. Overlap asthma and COPD 3. Presence of any condition that may limit mobility or physical performance due to factors other than asthma

Countries

Spain, Switzerland

Contacts

Public ContactSarah Koch
sarah.koch@unibas.ch+41 61 207 47 49

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026