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The effect of changing the length and thickness of the free gingival graft on palatal wound healing

Effect of graft dimensions on palatal wound re-epithelialization evaluated by toluidine blue stain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN15205513
Enrollment
64
Registered
2020-08-27
Start date
2018-09-08
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mucogingival problems qualifying them for surgery: thin biotype, a narrow zone of keratinized gingiva (=1 mm) and multiple gingival recession on the facial aspect of the mandibular anterior area Oral Health

Interventions

Following enrollment, participants are assigned to treatment groups using balanced block randomization. The surgeon, the observers and the patients are blinded. To meet the assumptions of randomizatio

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Older than 20 years 2. Presenting bilateral class I or II Miller gingival recession in the mandibular incisor region 3. Included teeth are vital and have no caries or restorations 4. Plaque and the gingival index scores less than 1 5. Systematically healthy and non-smokers

Exclusion criteria

Exclusion criteria: 1. Periodontal probing depth higher than 3 mm 2. Patient receiving medical therapy that interferes with wound healing process 3. Pregnant and lactating woman 4. Patient with a previous surgical procedure in the study area and patients undergoing orthodontic therapy

Design outcomes

Primary

MeasureTime frame
Re-epithelialization assessed using Toluidine Blue staining on the 7th, 14th, 21st, 28th, 35th, 42nd, 48th and 54th day post-surgery

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

Syria

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026