Measuring HIV-related mortality during surveys in Africa

Feasibility of measuring HIV-related mortality during population-based surveys in African countries: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN15197669

Enrollment

490

Registered

2018-10-12

Start date

2018-10-10

Completion date

Unknown

Last updated

2020-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV status of deceased sibling Infections and Infestations Human immunodeficiency virus [HIV] disease

Interventions

The trialists will enroll a sample of individuals aged 15-59 years old who have ever resided in the Karonga Health and Demographic Surveillance Systems (KHDSS) area and whose deceased sibling death wa

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 15-59 years old at the time of the study 2. Residing in the Karonga Health and Demographic Surveillance System (HDSS) area

Exclusion criteria

Exclusion criteria: 1. Younger than 15 years old at the time of enrollment 2. Older than 59 years old at the time of enrollment 6. Not residing in the Karonga Health and Demographic Surveillance System (HDSS) area

Design outcomes

Primary

Measure	Time frame
1. Sensitivity in recording the HIV status of deceased siblings in the ACASI and face-to-face groups. Sensitivity is defined as the proportion of HIV positive deaths according to KHDSS that were correctly reported as such by survey respondents. 2. Specificity in recording the HIV status of deceased siblings in the ACASI and face-to-face groups. Specificity is defined as the proportion of HIV-negative deaths according to KHDSS that were correctly reported as such by survey respondents. There will be one planned study visit per participant, with no planned follow-up. As such the outcomes will be measured at the one study visit. The trialists will measure the level of agreement between survey data and KHDSS data using Cohen’s Kappa in each study arm.	—

Measure

Time frame

1. Sensitivity in recording the HIV status of deceased siblings in the ACASI and face-to-face groups. Sensitivity is defined as the proportion of HIV positive deaths according to KHDSS that were correctly reported as such by survey respondents. 2. Specificity in recording the HIV status of deceased siblings in the ACASI and face-to-face groups. Specificity is defined as the proportion of HIV-negative deaths according to KHDSS that were correctly reported as such by survey respondents. There will be one planned study visit per participant, with no planned follow-up. As such the outcomes will be measured at the one study visit. The trialists will measure the level of agreement between survey data and KHDSS data using Cohen’s Kappa in each study arm.

—

Secondary

Measure	Time frame
1. The sensitivity/specificity of the survey in recording the respondent's own HIV status 2. The amount of time spent answering HIV-related questions, as measured internally by ODK 3. The accuracy of the enhanced questionnaire in assessing the engagement of deceased siblings identified as HIV-infected on the HIV care cascade There will be one planned study visit per participant, with no planned follow-up. As such the outcomes will be measured at the one study visit.	—

Measure

Time frame

1. The sensitivity/specificity of the survey in recording the respondent's own HIV status 2. The amount of time spent answering HIV-related questions, as measured internally by ODK 3. The accuracy of the enhanced questionnaire in assessing the engagement of deceased siblings identified as HIV-infected on the HIV care cascade There will be one planned study visit per participant, with no planned follow-up. As such the outcomes will be measured at the one study visit.

—

Countries

Malawi

Contacts

Public ContactStephane Helleringer

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026