Hypertension and subsequent development of other long-term conditions Circulatory System
Conditions
Interventions
A stepped-wedge cluster randomised controlled trial in 216 GP practices (clusters) within eight Integrated Care Systems (ICSs) in England over 4 years.
In year one, all GP practices will offer usual
Sponsors
Chelsea and Westminster Hospital NHS Foundation Trust
Eligibility
Sex/Gender
All
Age
18 Years to 120 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with hypertension and aged 18 years or over. 2. Individuals who are aged 80 years and older are eligible to access the programme if their clinician referrer provides written confirmation that the referrer perceives the benefits of the study outweigh any potential risks of participating in a weight loss programme for that individual.
Exclusion criteria
Exclusion criteria: 1. Individuals with diabetes or non-diabetic hyperglycaemia 2. Individuals with an eating disorder 3. Individuals with severe/moderate frailty 4. Individuals who have undergone bariatric surgery in the last 2 years 5. Individuals aged under 18 years 6. Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of associated long-term conditions in individuals with hypertension within participating GP practices measured through the Bridges to Health Segmentation dataset, an existing dataset held within NHS England, at the end of each year in the study (years 1, 2, 3 and 4). Associated conditions have been defined as atrial fibrillation, cerebrovascular disease, chronic kidney disease, chronic liver disease, chronic pain, coronary heart disease, depression, diabetes, heart failure, osteoarthritis, peripheral vascular disease and physical disability. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The incidence of long-term conditions (associated and not associated conditions) in individuals with hypertension within participating GP practices measured through the Bridges to Health Segmentation dataset at the end of years 1, 2, 3 and 4. In subgroup analyses of those with hypertension who are referred: 2. Weight change at the end of the programme measured using the Healthier You Minimum Dataset (MDS). Weight measurements will be taken on attendance of each intervention session, with weight change calculated by taking the difference between the first weight measurement and the weight for the last intervention session attended. 3. Completion (or non-completion) of the programme: completion is defined as attendance of 60% or more of the intervention sessions. Measured using the Healthier You Minimum Dataset (MDS). 4. Incidence of associated conditions measured through the Bridges to Health Segmentation dataset at the end of years 2, 3 and 4. Associated conditions have been defined as atrial fibrillation, cerebrovascular disease, chronic kidney disease, chronic liver disease, chronic pain, coronary heart disease, depression, diabetes, heart failure, osteoarthritis, peripheral vascular disease and physical disability. Not associated conditions have been defined as alcohol dependence, asthma, bronchiectasis, cancer, cancer, COPD, epilepsy, inflammatory bowel disease, frailty, multiple sclerosis, neurological organ failure, osteoporosis, Parkinson's disease, pulmonary heart disease, rheumatoid arthritis, sarcoidosis, serious mental illness, severe interstitial lung disease. | — |
Countries
England, United Kingdom
Contacts
Public ContactJonathan Valabhji
Outcome results
None listed