Post-natal depression Mental and Behavioural Disorders
Conditions
Sponsors
University College London
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older 2. Female 3. Postnatal depression as indicated by a score of 12 or more on the PHQ-9 at baseline 4. Mother with an infant aged 6 - 35 weeks old at the time of screening
Exclusion criteria
Exclusion criteria: 1. Mothers with psychotic conditions including bipolar disorder, anorexia nervosa or substance dependence 2. Mothers whose babies have severe physical health problems or neurodevelopmental problems will also be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infant’s cognitive development measured using the Malawi Developmental Assessment Tool (MDAT) (Gladstone et al. 2010), at 52 weeks (T6) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Severity of depression measured using the Patient Health Questionnaire – depression module (PHQ-9) (Kroenke & Spitzer, 2002) at baseline (T1), 8 weeks (T2), 13 weeks(T3), 24 weeks (T4), 36 weeks (T5) and 52 weeks (T6) 2. Family circumstances assessed using the family circumstances questionnaire at baseline (T1), 13 weeks (T3) and 52 weeks (T6) 3. Maternal sensitivity and indicators of family care assessed using the Family Care Indicator (FCI) (Kariger et al., 2012) at baseline (T1), 8 weeks (T2), 13 weeks(T3), 24 weeks (T4), 36 weeks (T5) and 52 weeks (T6) 4. Early childhood development outcomes measured using the Caregiver Reported Early Development Index (CREDI) long form (McCoy et al., 2018) at baseline (T1), 13 weeks (T3) and 36 weeks (T5) 5. Anxiety measured using the General Anxiety Disorder-7 (GAD-7) (Spitzer et al., 2006) at baseline (T1), 8 weeks (T2), 13 weeks(T3), 24 weeks (T4), 36 weeks (T5) and 52 weeks (T6) 6. Sleep measured using the Sleep Condition Indicator (SCI) (Espie et al., 2014) at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4), 36 weeks (T5) and 52 weeks (T6) 7. Infant’s sleep measured using the Brief Infant Sleep Questionnaire – Revised Short form (BISQ) (Mindell et al., 2019) at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4), 36 weeks (T5) and 52 weeks (T6) 8. Infant’s physical health measured using the infant physical health questionnaire at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4), 36 weeks (T5) and 52 weeks (T6) 9. Breastfeeding assessed using the breastfeeding outcome measure at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4), 36 weeks (T5) and 52 weeks (T6) 10. Social isolation assessed using the Lubben Social Network Scale (LSNS-6) (Lubben & Gironda, 2000) at baseline (T1), 13 weeks (T3) and 52 weeks (T6) 11. Relationship satisfaction measured using the Couple Satisfaction Index (CSI-4) (Funk & Rogge, 2007) at baseline (T1), 13 weeks (T3) and 52 weeks (T6) 12. Health out | — |
Countries
Kenya, Lebanon
Contacts
Public ContactElizabeth ;Ciara Simes;O'Donnell
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Outcome results
None listed