Angle-closure glaucoma Eye Diseases
Conditions
Interventions
This is a diagnostic accuracy study. The tests will be used for triage. The study aims to propose a novel patient pathway. To evaluate the diagnostic performance of two non-contact diagnostic tests co
Sponsors
Queen's University Belfast
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adults (=18 years) referred from community optometry to hospital eye services with suspected angle closure glaucoma
Exclusion criteria
Exclusion criteria: Unable to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of the new pathway to detect angle-closure glaucoma measured using standard formulas and pre-specified criteria for test positivity. All tests will be done at the same clinic visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| The following outcome measures will be assessed and recorded in patient notes at the same clinic visit: 1. Positive/negative likelihood ratios for angle-closure glaucoma development measured using standard formulas 2. Concordance measured using standard formulas 3. Long-term health and cost outcomes measured using a Markov model run over an expected lifetime time horizon 4. Proportion of patients requiring subsequent clinical assessment by ophthalmologist measured using descriptive statistics 5. Proportion of patients unable to undergo tests and of tests of inadequate quality measured using descriptive statistics 6. Health-related quality of life measured using the EuroQol Health Questionnaire (EQ-5D-5L) | — |
Countries
England, Northern Ireland, Scotland, United Kingdom, Wales
Contacts
Public ContactMary Guiney
Outcome results
None listed