Gynoid lipodystrophy (Cellulite) Skin and Connective Tissue Diseases Gynoid lipodystrophy (Cellulite)
Conditions
Interventions
Participants are given an hypertonic topical product with draining action (HTC cream) that contains NaCl 13%, escine, caffeine and beta-sytosterol. They are asked to apply it once daily on their thigh
Sponsors
Difa Cooper
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Women aged 18-65 years 2. Have grade II-IV gynoid lipodystrophy
Exclusion criteria
Exclusion criteria: 1. Previous treatment (within 2 months of the study period) for cellulite (topical or oral) 2. Positive history for lower limbs venous or lymphatic insufficiency 3. Pregnancy or breast feeding 4. Positive history of allergic contact dermatitis to any of the component of the cream
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Thigh circumferential is measured using a flexible measuring ruler with the participant in standing position and performing the measurement up to 25 cm from the superior pole of the patella at baseline, one and two months 2. Computer-analysis of skin profilometry of a pre-specified target area (in general in the zone above the trochanteric eminence or gluteal zone) evaluated by means of Antera 3D CS (Miravex, Dublin, Ireland) at baseline and two months | — |
Secondary
| Measure | Time frame |
|---|---|
| Cellulite (skin appearance) are measured using the orange peel severity score (0 to 5) before and after the pinch test at baseline, one and two months. | — |
Countries
United Kingdom
Outcome results
None listed