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A comparison of sea-cucumber based gel to conventional hydrogels in wound healing

A prospective case-control comparative study to evaluate the efficacy of Gamat gel in comparison with hydrogel in treatment of skin graft donor sites

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN15108764
Enrollment
25
Registered
2018-02-16
Start date
2016-12-29
Completion date
Unknown
Last updated
2018-11-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin graft donor site wounds Not Applicable

Interventions

This is a prospective, single-blinded, comparative clinical trial involving patients in Hospital Universiti Sains Malaysia with partial thickness wounds which were created as an after effect of skin g

Sponsors

Hospital Universiti Sains Malaysia
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All patients with partial thickness wounds after split-skin graft harvesting 2. This thickness is at 0.2 mm (0.008 inch); harvested with a specified dermatome 3. Skin-graft donors > 25cm2 wide 4. Consented patients 5. Patients compliant to the treatment protocol

Exclusion criteria

Exclusion criteria: 1. Accidental full thickness harvesting 2. Non-compliant patient, causing dressing to dislodge 3. Patients with history of allergy to seafood/ sea cucumber 4. Patients with uncontrolled diabetes mellitus, on steroid medications or who are immunocompromised 5. Pregnancy 6. Patient with skin pathology (eczema etc)

Design outcomes

Primary

MeasureTime frame
Wound epithelialization, assessed by clinical judgment and calculated as percent of surface of wound epithelialized at day 10, 14 and 21 after intervention

Secondary

MeasureTime frame
1. Pain and pruritus assessed with visual analogue scale at day 10, 14 and 21 2. Scar quality assessed with modified Vancouver scar scale (MVSS) at follow up (week 6 to 9)

Countries

Malaysia

Contacts

Public ContactAdzim Poh Yuen Wen

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026