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Brief intervention in patients with esophageal varices (abnormal, enlarged veins in the tube that connects the throat and stomach)

Effects of a brief intervention on mortality in patients with liver cirrhosis complicated by esophageal varices – a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN15107567
Enrollment
84
Registered
2021-04-24
Start date
2013-04-09
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol use among patients with liver cirrhosis Digestive System Fibrosis and cirrhosis of liver

Interventions

Brief intervention (a psychological counselling technique based on motivational interviewing) Following written informed consent and screening, included patients are subject to comput
developing discrepancy
rolling with resistance, avoiding argument
and supporting efficacy to change. All patients are followed by time-line follow back telephone interviews by a study nurse every third month for two years and patients report alcohol

Sponsors

Capio S:t Göran Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients over the age of 18 with any chronic liver disease with esophageal varices diagnosed by endoscopy or computer tomography at Capio S:t Görans Hospital, Stockholm

Exclusion criteria

Exclusion criteria: Hepatic encephalopathy too severe for interviewing

Design outcomes

Primary

MeasureTime frame
Overall mortality rate is measured from the medical files which are based on the National Public Death Rate. The study is censored at the time of death or at the end of the study period. Death is registered even if the patients have dropped out of the study.

Secondary

MeasureTime frame
1. Alcohol use measured using ASI, AUDIT at inclusion and TLFB on follow-up 2. Alcohol consumption after the intervention is explored as change in alcohol consumption between baseline and follow-up. Consumption are defined in terms of standard drinks containing 14 grams of alcohol

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026