Orthostatic hypotension (OH) Circulatory System Orthostatic hypotension (OH)
Conditions
Interventions
Current interventions as of 17/09/2018:
Stage 1
After provision of informed consent, participants have their height and weight recorded before being invited to lie down
Sponsors
The Newcastle upon Tyne Hospitals NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 60 years or above 2. Clinical diagnosis of orthostatic hypotension (confirmed with a postural drop in systolic/diastolic blood pressure of at least 20/10 mmHg within 3 minutes of standing upright from a supine position). 3. Able to stand upright
Exclusion criteria
Exclusion criteria: 1. Age below 60 years 2. Dysphagia or previous episode of aspiration 3. Peripheral vascular disease or lower limb ulceration 4. Any contra-indication to bolus water drinking (such as a fluid restriction, cardiac/renal/liver failure) 5. Unable to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postural systolic blood pressure drop is measured using non-invasive, beat-to-beat monitoring (Taskforce Monitor, CNSystems) at baseline (before intervention) and then during each intervention (visit 1 and visit 2). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Postural diastolic blood pressure drop is measured using non-invasive, beat-to-beat monitoring (Taskforce Monitor, CNSystems) at baseline (before intervention) and then during each intervention (visit 1 and visit 2) 2. Symptoms are measured using the Orthostatic Hypotension Questionnaire Symptom score at baseline and then immediately after orthostatic challenge with each intervention (visit 1 and 2) 3. Acceptability of and barriers to therapy are measured using data from qualitative interviews at visit 3 | — |
Countries
England, United Kingdom
Contacts
Public ContactRuth Pearce
Outcome results
None listed