Chickenpox Infections and Infestations
Conditions
Interventions
Inpatient arm:
We will recruit patients with with acute varicella or secondary complications requiring admission to hospital. After informed consent they (child and both carers) will be asked to comp
Sponsors
University of Bristol
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male or Female, less than 18 years old. 2. Hospital arm: Currently have chickenpox or have had it during the last 21 days (12m for stroke). 3. Community arm: History of close exposure to active case of chickenpox or diagnosis of early disease 4. Informed consent obtained from the parent(s) / guardian with assent in children >6 years.
Exclusion criteria
Exclusion criteria: 1. Only those for whom admission is felt to be clinically unrelated to recent varicella (e.g. injuries / new malignant diagnosis) should be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total QALY loss due to varicella in children and carers, for child assessed with CHU9 & EQ5D-5L and for parent with EQ5D-5L. For inpatient arm this is measured daily until discharge, once weekly for first month and then again at 6m. For community arm this is measured alternate days (although there is a diary every day) | — |
Secondary
| Measure | Time frame |
|---|---|
| We will collect data on disease severity using a previously validated assessment of varicella symptoms tool (Vázquez et al 2001), demographics, healthcare use, illness within the family unit and missed work/education days. We will estimate the financial and societal costs for families through a daily diary inquiring about medication use, additional childcare costs and days of work missed. | — |
Countries
England, Portugal, United Kingdom
Outcome results
None listed