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The Second Heart Program: an intervention for individuals who have infective endocarditis who inject drugs

The Second Heart Program: a peer-focused, multidisciplinary harm reduction intervention to improve outcomes for people who inject drugs after admission for infective endocarditis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN14968657
Enrollment
40
Registered
2021-01-13
Start date
2020-12-01
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

People who inject drugs after admission for infective endocarditis Circulatory System Acute and subacute infective endocarditis

Interventions

The proposed innovation (Second Heart Program) is a peer-focused, multidisciplinary harm reduction intervention strategy to address gaps in the current management of PWID with IE. The Second Heart Pro

Sponsors

McMaster University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age 18 or older 2. Able to provide informed consent in English 3. Admitted to either St Joseph’s Hospital or Hamilton General Hospital located in Hamilton with the diagnosis of infective endocarditis at the time of recruitment 4. History of injection drug use within 3 months of recruitment

Exclusion criteria

Exclusion criteria: 1. Does not live in the City of Hamilton

Design outcomes

Primary

MeasureTime frame
1. Recruitment rate recorded as the number of eligible participant who consent to participate in the study by 12 months 2. Attrition rate recorded as the number of participants who consent to participate that remain in the study until the end of follow up at 12 months

Secondary

MeasureTime frame
1. Patient information (including descriptive demographic data, social determinants of health, medical history, substance use history, access to harm reduction and community resources, and treatment plan and patient goals) will be collected by a combination of self-report and electronic medical record chart review at baseline and 12-months post-discharge 2. Resource feasibility outcomes (number and nature of connections with the peer support worker and systems navigator) will be tracked in an appointment tracking file with every contact they come into with patient. Program costs will be extracted from financial reports yearly 3. Management feasibility outcomes (number and nature of challenges in data collection) will be recorded by a memo note ongoing throughout the study 4. Scientific feasibility outcomes (reinfection, readmission, and reintervention rate at 1, 3, 6, and 12-months, 1-year post-discharge mortality rate, number of touch points with cardiovascular surgery, cardiology, infectious disease, systems navigator, primary care physician, addictions services in hospital and 1-year post-discharge) will be extracted from the electronic medical record for each patient. These outcomes will also be collected via self-report survey at 1, 3, 6, and 12 months 5. Perceived strengths, weaknesses, opportunities, and threats of the program and perceived acceptability will be explored via 1-on-1 semi-structured interviews with patients (at 3- and 12-months post-discharge), peer support workers, addiction medicine physicians, systems navigator, primary care physician, peer support worker coordinator at 12 months. Clinicians who co-manage these patients during their in-patient stay (cardiovascular surgery, internal medicine, cardiology) and other community partners (primary care physicians, addictions care providers) will be asked to complete an open-ended survey to assess their perceived strengths, weaknesses, opportunities, and threats of the program, as well as acceptabil

Countries

Canada

Contacts

Public ContactAlisha Atri
atria1@mcmaster.ca+1 (0)905 525 9140 x21572

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 14, 2026