Study of correlation between the extent of spread of cerebro-spinal fluid measured using Magnetic Resonance Imaging and the severity of headache following accidental dural puncture during epidural catheter placement for labour analgesia

Does Magnetic Resonance Imaging (MRI) correlate with severity of headache following accidental dural puncture (ADP) during epidural catheter placement for labour analgesia?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14959004

Enrollment

Registered

2018-01-08

Start date

2013-09-01

Completion date

Unknown

Last updated

2021-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Specialty: Reproductive health and childbirth, Primary sub-specialty: Reproductive and Sexual Medicine

Interventions

Participants receiving epidurals for labour analgesia, who sustain an accidental dural puncture (ADP), would undergo clinical management according to the local departmental protocols as usual. If they

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: All adult (>16 years of age) women in labour who received an epidural / CSE for pain relief and sustained an observed ADP with an epidural needle.

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Unsuitable for MRI (e.g. metal implants, pace maker etc) 3. Pre-existing headaches / migraine, spinal surgery 4. Spine deformity or anomalies

Design outcomes

Primary

Measure	Time frame
Presence, or otherwise, of a statistically significant positive correlation between the extent of spread of cerebro-spinal fluid measured using Magnetic Resonance Imaging and the severity of PDPH according to a carefully designed scoring system developed by the study team.	—

Secondary

Measure	Time frame
Incidental findings on the images measured using Magnetic Resonance Imaging.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 16, 2026