Burn wounds Skin and Connective Tissue Diseases Burn wounds
Conditions
Interventions
In patients with burn wounds, one area is treated with excision of the burn and application of a split skin graft (standard care) and in a comparable area with burn wounds, autologous platelet rich pl
Sponsors
Red Cross Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18 years and older 2. Admitted at the Dutch burn centre in Beverwijk with a full thickness or deep dermal burn wounds with a surface area of at least 2% total body surface area (TBSA) who needed transplantation with a split skin graft
Exclusion criteria
Exclusion criteria: 1. Likely problems, in the judgment of the investigators, with maintaining follow-up 2. Insufficient comprehension of the Dutch language to understand a rehabilitation program and other treatment information in the judgment of the attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Take rate (percentage of the graft that appeared to be vital and showed good adherence to the wound bed) and epithelialization rate (percentage of the wound closure by either skin graft or outgrowth from graft or wound edges) of the split skin grafts of area A and B at day 5-7 post surgery, as judged by experienced burn clinicians. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Pain and itch scores of area A and B after surgery until discharge measured using Visual Analogue Thermometer (VAT) score 2. Bacterial status of area A and B before surgery and twice weekly until discharge with swabs 3. Scar quality at 3, 6 and 12 months of area A and B measured by the POSAS scar assessment scales, Dermaspectrometer (scar color and pigmentation) and Cutometer (scar elasticity) | — |
Countries
Netherlands
Outcome results
None listed