Bacterial infection Infections and Infestations
Conditions
Interventions
MR-proADM and ImmunoXpert analysis of blood samples of children recruited to the BATCH trial (ISRCTN11369832) who have been hospitalised with suspected or confirmed bacterial infection, randomised to
Sponsors
University of Liverpool
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Same as the BATCH trial (ISRCTN11369832)
Exclusion criteria
Exclusion criteria: Same as the BATCH trial (ISRCTN11369832)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Collected from patient notes up to and including day 28, or until discharge: 1. Time until IV antibiotic therapy is stopped 2. MR-proADM and ImmunoXpert scores at baseline will define subgroups for the primary comparison, and serial measurements for additional analyses | — |
Secondary
| Measure | Time frame |
|---|---|
| Collected from patient notes up to and including day 28, or until discharge: 1. Total duration of antibiotics (oral and IV) 2. Time to switch from broad-spectrum to narrow-spectrum antibiotics 3. Time to discharge from hospital 4. Suspected adverse drug reactions measured using the Liverpool Causality Assessment tool 5. Hospital-acquired infection up to Day 28 | — |
Countries
England, United Kingdom
Contacts
Public ContactCherry-Ann Waldron
Outcome results
None listed