Can additional bowel preparation improve the detection of disease in the bowel using ultrasound?

ENPIC (ENhanced Preparation In Colonic) Ultrasound: a study protocol for a single centre, non-randomised, single-arm, prospective pilot study to investigate the accuracy of Ultrasound in the assessment of the colon when combined with bowel preparation

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14918879

Enrollment

Registered

2024-06-19

Start date

2024-09-01

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Accuracy of ultrasound in the assessment of the colon when combined with bowel preparation Digestive System

Interventions

This is a single-centre, non-randomised, single-arm, prospective pilot study to investigate the accuracy of ultrasound in the assessment of the colon when combined with bowel preparation. Patients un

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 years or over 2. Undergoing CTC (for screening or symptomatic indication) 3. Completion of CTC preparation 4. Able to give written informed consent

Exclusion criteria

Exclusion criteria: 1. Aged <18 years 2. Unable to adequately complete standard CTC preparation 3. Pregnant

Design outcomes

Primary

Measure	Time frame
The sensitivity of accuracy of transabdominal ultrasound (TAUS) in identifying colonic pathology measured using data collected during TAUS compared with a consensus reference standard (same-day computed tomography colonography [CTC]) at one timepoint	—

Secondary

Measure	Time frame
1. The specificity of ultrasound diagnosis in characterising colonic pathology measured using data collected during TAUS compared with a consensus reference standard (same-day computed tomography colonography [CTC]) at one timepoint 2. The identification rate of the appendix (sensitivity) and any associated pathology of the appendix measured using data collected during TAUS compared with a consensus reference standard (same-day computed tomography colonography [CTC]) at one timepoint 3. Compare ultrasound users: 3.1. Years of experience in ultrasound as self-reported by ultrasound user at baseline 3.2. Type of ultrasound training as self-reported at baseline	—

Measure

Time frame

1. The specificity of ultrasound diagnosis in characterising colonic pathology measured using data collected during TAUS compared with a consensus reference standard (same-day computed tomography colonography [CTC]) at one timepoint 2. The identification rate of the appendix (sensitivity) and any associated pathology of the appendix measured using data collected during TAUS compared with a consensus reference standard (same-day computed tomography colonography [CTC]) at one timepoint 3. Compare ultrasound users: 3.1. Years of experience in ultrasound as self-reported by ultrasound user at baseline 3.2. Type of ultrasound training as self-reported at baseline

—

Countries

England, United Kingdom

Contacts

Public ContactRuth Reeve

ruth.reeve@porthosp.nhs.uk+44 (0)2392 285153

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026