Analgesia for patients undergoing extensive abdominal laparoscopic surgeries Surgery
Conditions
Interventions
The study design is a prospective interventional trial compared to a historical cohort, conducted in a single center. The historical cohort will be constituted of patients recruited in the control gro
Sponsors
Integrated University Health and Social Services Centre of East Montreal Island
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patient from 18 to 80 years old 2. ASA 1-3 3. Laparoscopic surgery (including general surgery, gynecology, urology), a small abdominal incision (less than 5 cm) will be tolerated.
Exclusion criteria
Exclusion criteria: 1. Patient refusal 2. Chronic use of opioids 3. Allergy to medication used in the trial 4. Pregnant or breastfeeding women 5. Contraindications to dexmedetomidine 6. Bradycardia, arrythmia or pacemaker, severe ventricular dysfunction
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1. Mean intraoperative blood pressure and heart rate measured using an anesthesia monitor during the intraoperative period 2. Intraoperative episodes of high blood pressure, low blood pressure, tachycardia, and bradycardia measured using an anesthesia monitor during the intraoperative 3. Requirements of rescue medications to maintain blood pressure and heart rate within the limits previously described measured using the anesthesia record during the intraoperative period 4. Intraoperative nociception level (NOL) index measured using a NOL monitor during the intraoperative period 5. Time from the end of surgery to extubation measured using the anesthesia record at one timepoint at the end of surgery 6. Total propofol consumption throughout the surgery in mg·kg?¹·h?¹ measured using the anesthesia record during the intraoperative period 7. Postoperative morphine equivalent consumption measured using the medication record at post-anesthesia care unit (PACU) stay 8. Pain scores measured using the Visual Analogue Scale (VAS) at PACU stay from arrival to discharge 9. Adverse events in PACU: hypotension, bradycardia, PONV measured using PACU records at PACU stay 10. Length of stay in PACU measured using the PACU record at PACU stay 11. Quality of Recovery (QoR) index measured using the QoR questionnaire at 24h post-op 12. Pain scores measured using the numeric rating scale (NRS) at 24h post-op 13. Hospital length of stay measured using the hospital record at discharge | — |
Countries
Canada
Contacts
Public ContactNadia Godin
Outcome results
None listed