A study analyzing if a healthy diet improves the taste preference profile and flavor perception

Effect of the intervention with a healthy diet on the flavor preference profile and improvement of taste and odor perception in a Mediterranean population: A randomized and controlled clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14827027

Enrollment

200

Registered

2021-12-13

Start date

2021-12-21

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Improving flavor perception and preferences in the general population Not Applicable

Interventions

Participants (n=200) will be randomized 1:1 to 2 arms (intervention and control groups) using an online tool (compute program). One study arm (n=100 participants) will receive the intervention consist

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults from the general population (50% women) 2. Age range of 25 to 75 years 3. Body mass index (BMI) of 25 to 35 kg/m²

Exclusion criteria

Exclusion criteria: Those individuals who do not meet the inclusion criteria or who present the following conditions: 1. Allergy to the tastants or to any food recommended in the healthy dietary pattern 2. Pregnant or lactating women 3. Infectious diseases 4. Kidney or liver diseases 5. Cancer 6. Other relevant pathologies that could bias the study

Design outcomes

Primary

Measure	Time frame
Measured at baseline and 6 months: 1. Flavor preferences (all the tastes and selected odors will be measured using the 9-item hedonic scales) 2. Taste perception: intensity rating test with prototypic tastants for (bitter, sweet, sour, umami, and salty) at different concentrations will be carried out in the laboratory 3. Odor perception tests using the "NHANES Odor Test" (US National Health and Nutrition Examination Survey) protocol	—

Measure

Time frame

Measured at baseline and 6 months: 1. Flavor preferences (all the tastes and selected odors will be measured using the 9-item hedonic scales) 2. Taste perception: intensity rating test with prototypic tastants for (bitter, sweet, sour, umami, and salty) at different concentrations will be carried out in the laboratory 3. Odor perception tests using the "NHANES Odor Test" (US National Health and Nutrition Examination Survey) protocol

—

Secondary

Measure	Time frame
1. Anthropometric measures (by bioimpedance) at baseline and 6 months in both groups. 2. Blood pressure and heart rate parameters, at baseline and after 6 months in both groups by standard procedures 3. The level of adherence to the Mediterranean Diet through the 17-ite questionnaire at baseline and at 6 months. 4. Food intake (by a FFC) at baseline and 6 months. 5. Physical activity measured using the short form of the Minnesota physical activity questionnaire at baseline. 6. Sleep characteristics measured using the Pittsburgh Sleep Quality Index questionnaire at baseline and at 6 months. 7. Chronotype at baseline, measured using the Horne and Östberg questionnaire. 8. Cognitive tests, measuring semantic and phonemic verbal capacity and average executive control, the Controlled Oral Word Association Test (COWAT), and the memory alteration test (T @ M) at baseline and after 6 months. 9. Quality of life (SF-36 or SF-12) at baseline and after 6 months.	—

Measure

Time frame

1. Anthropometric measures (by bioimpedance) at baseline and 6 months in both groups. 2. Blood pressure and heart rate parameters, at baseline and after 6 months in both groups by standard procedures 3. The level of adherence to the Mediterranean Diet through the 17-ite questionnaire at baseline and at 6 months. 4. Food intake (by a FFC) at baseline and 6 months. 5. Physical activity measured using the short form of the Minnesota physical activity questionnaire at baseline. 6. Sleep characteristics measured using the Pittsburgh Sleep Quality Index questionnaire at baseline and at 6 months. 7. Chronotype at baseline, measured using the Horne and Östberg questionnaire. 8. Cognitive tests, measuring semantic and phonemic verbal capacity and average executive control, the Controlled Oral Word Association Test (COWAT), and the memory alteration test (T @ M) at baseline and after 6 months. 9. Quality of life (SF-36 or SF-12) at baseline and after 6 months.

—

Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026